CTX-BLAST: context sensitive version of protein BLAST
نویسندگان
چکیده
UNLABELLED We present a software tool CTX-BLAST that incorporates contextual alignment model into the popular protein BLAST program. Our alignment tool allows us to investigate the effect of context-dependency in the protein alignment much more efficient than using previous dynamic algorithms. The software makes use of non-symmetric contextual substitution tables and calculates the statistical significance of a given alignment according to the contextual statistical model. AVAILABILITY CTX-BLAST is an open source software freely available from www.sourceforge.net/projects/CTX-BLAST. A program for statistical estimation of E-value parameters and the contextual substitution table CTX-BLOSUM62 are also provided. SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.
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عنوان ژورنال:
- Bioinformatics
دوره 23 13 شماره
صفحات -
تاریخ انتشار 2007